Proteolytic Modification of Cell Surface Macromolecules: Mode of Action in Stimulating Cell Growth

作者: Kenneth D. Noonan

DOI: 10.1016/S0070-2161(08)60753-4

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摘要: Publisher Summary This chapter discusses proteolytic modification of cell surface macromolecules. Itanalyzes strong evidence to implicate one or more membrane peptides glycopeptides as controlling element(s) in determining whether not a population will be stimulated divide the protease treatment surface. The also reviews for and against protease-induced transmembrane control division. It presents that is at least supportive concept peptide glycopeptide can initiate series intracellular events culminate effects proteolysis on growth state lymphocytes, thymocytes, fibroblasts. To introduce methodology concepts underlying use proteases modify structure, extensive work done area erythrocyte briefly reviewed chapter. point out some problems biologists must aware when are used stimulants

参考文章(168)
Victor B. Hatcher, Michael S. Wertheim, Choo Y. Rhee, Grace Tsien, Peter G. Burk, Relationship between cell surface protease activity and doubling time in various normal and transformed cells. Biochimica et Biophysica Acta. ,vol. 451, pp. 499- 510 ,(1976) , 10.1016/0304-4165(76)90145-8
GEORGE S. JOHNSON, WILLIE D. MORGAN, IRA PASTAN, Regulation of Cell Motility by Cyclic AMP Nature. ,vol. 235, pp. 54- 56 ,(1972) , 10.1038/235054A0
B. M. SEFTON, H. RUBIN, Release from Density Dependent Growth Inhibition by Proteolytic Enzymes Nature. ,vol. 227, pp. 843- 845 ,(1970) , 10.1038/227843A0
K. M. Yamada, S. S. Yamada, I. Pastan, Cell surface protein partially restores morphology, adhesiveness, and contact inhibition of movement to transformed fibroblasts Proceedings of the National Academy of Sciences of the United States of America. ,vol. 73, pp. 1217- 1221 ,(1976) , 10.1073/PNAS.73.4.1217
Domenico Mazzei, Carlo Novi, Claudio Bazzi, MITOGENIC ACTION OF TRYPSIN AND CHYMOTRYPSIN The Lancet. ,vol. 288, pp. 232- ,(1966) , 10.1016/S0140-6736(66)92526-8
Eric Martz, Malcolm S. Steinberg, The role of cell-cell contact in ?contact? inhibition of cell division: A review and new evidence Journal of Cellular Physiology. ,vol. 79, pp. 189- 210 ,(1972) , 10.1002/JCP.1040790205
Rochelle Hirschhorn, Judith Grossman, Walter Troll, Gerald Weissmann, The effect of epsilon amino caproic acid and other inhibitors of proteolysis upon the response of human peripheral blood lymphocytes to phytohemagglutinin Journal of Clinical Investigation. ,vol. 50, pp. 1206- 1217 ,(1971) , 10.1172/JCI106598
R. Pollack, R. Risser, S. Conlon, D. Rifkin, Plasminogen activator production accompanies loss of anchorage regulation in transformation of primary rat embryo cells by simian virus 40. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 71, pp. 4792- 4796 ,(1974) , 10.1073/PNAS.71.12.4792