Telomerase Inhibitors and Activators: Pharmaceutical Importance

Iffet Sahin F, Darcansoy Iseri O, Yurtcu E, Effects of silymarin and silymarin-doxorubicin applications on telomerase activity of human hepatocellular carcinoma cell line HepG2. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. ,vol. 20, pp. 555- 561 ,(2015)

Fujiko Oh-hashi, Tomoko Oh-hara, Kenneth Chan, Jeffrey Johnston, Takashi Tsuruo, Wan Yong Feng, Imad Naasani, Blocking telomerase by dietary polyphenols is a major mechanism for limiting the growth of human cancer cells in vitro and in vivo. Cancer Research. ,vol. 63, pp. 824- 830 ,(2003)

Didem Turgut, Ahu Soyocak, Inhibiting Telomerase Activity and Inducing Apoptosis in Cancer Cells by Several Natural Food Compounds InTech. ,(2012) , 10.5772/53226

Li Sun, Xu Wang, Effects of allicin on both telomerase activity and apoptosis in gastric cancer SGC-7901 cells World Journal of Gastroenterology. ,vol. 9, pp. 1930- 1934 ,(2003) , 10.3748/WJG.V9.I9.1930

Giampietro Ravagnan, M. Tricarico, E. Bonmassar, A. Cottarelli, M. P. Fuggetta, G. Lanzilli, R. Falchetti, Effect of resveratrol on proliferation and telomerase activity of human colon cancer cells in vitro. Journal of Experimental & Clinical Cancer Research. ,vol. 25, pp. 189- 193 ,(2006)

Goro Kajiyama, Hidetoshi Tahara, Toshinori Ide, Ryo Nakashio, Eiichi Tahara, Mikiya Kitamoto, Jerry W. Shay, Toshio Nakanishi, Telomerase Activity in Human Liver Tissues: Comparison between Chronic Liver Disease and Hepatocellular Carcinomas Cancer Research. ,vol. 55, pp. 2734- 2736 ,(1995)

L Xia, X X Wang, X S Hu, X G Guo, Y P Shang, H J Chen, C L Zeng, F R Zhang, J Z Chen, Resveratrol reduces endothelial progenitor cells senescence through augmentation of telomerase activity by Akt-dependent mechanisms British Journal of Pharmacology. ,vol. 155, pp. 387- 394 ,(2009) , 10.1038/BJP.2008.272

James R. Mitchell, Emily Wood, Kathleen Collins, A telomerase component is defective in the human disease dyskeratosis congenita Nature. ,vol. 402, pp. 551- 555 ,(1999) , 10.1038/990141

Ashish T Baviskar, Chetna Madaan, Ranjan Preet, Purusottam Mohapatra, Vaibhav Jain, Amit Agarwal, Sankar K Guchhait, Chanakya N Kundu, Uttam C Banerjee, Prasad V Bharatam, None, N-Fused Imidazoles As Novel Anticancer Agents That Inhibit Catalytic Activity of Topoisomerase IIα and Induce Apoptosis in G1/S Phase Journal of Medicinal Chemistry. ,vol. 54, pp. 5013- 5030 ,(2011) , 10.1021/JM200235U

Liang Liu, Serene Lai, Lucy G. Andrews, Trygve O. Tollefsbol, Genetic and epigenetic modulation of telomerase activity in development and disease Gene. ,vol. 340, pp. 1- 10 ,(2004) , 10.1016/J.GENE.2004.06.011