作者: Weigang Wang , Robert Eddy , John Condeelis
DOI: 10.1038/NRC2148
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摘要: Recent evidence indicates that metastatic capacity is an inherent feature of breast tumours and not a rare, late acquired event. This has led to new models metastasis. The interpretation expression-profiling data in the context these identified cofilin pathway as major determinant studies indicate overall activity pathway, any single gene within determines invasive phenotype tumour cells. These results predict inhibitors directed at output will have therapeutic benefit combating