Expression of connexin29 and 32 in the penumbra region after traumatic brain injury of mice.

摘要: Connexins (Cx) are transmembrane proteins forming vertebrate gap junction channels for direct cell-cell communication. We found that the expressions of two Cx family members, Cx29 and Cx32, were progressively increased in sharp border injury penumbra regions after cryotraumatic brain injury. Although these Cxs expressed exclusively oligodendrocytes normal cerebral cortex, their astrocytes microglia localized border. Highly selective induction suggests altered may contribute to propagations injury-related and/ or regeneration signals acute