Challenges in Quantifying Digestion

作者: Robert Havenaar , Mans Minekus

DOI: 10.1007/978-3-030-03901-1_4

关键词:

摘要: This chapter discusses the challenges in relation to food and nutrient terminology, chemical analysis, human animal digestion studies as well those related vitro with static methods dynamic gastrointestinal models. Although it looks simple, using uniform terminology definitions science is first challenge. The same true for analysis determining concentrations of compounds samples from vivo studies. Effort has been taken by different institutes working groups standardize these challenges. Then comes challenge setting up studies, be clinical or Each type study its specific that should recognized before starting experiments. We discuss support researcher, but we do realize not all aspects are covered.

参考文章(55)
Mans Minekus, Phillipe Marteau, Robert Havenaar, Jos H.J. Huis in't Veld, A multicompartmental dynamic computer-controlled model simulating the stomach and small intestine Atla-alternatives To Laboratory Animals. ,vol. 23, pp. 197- 209 ,(1995) , 10.1177/026119299502300205
Thao T.P. Nguyen, Bhesh Bhandari, Julie Cichero, Sangeeta Prakash, A comprehensive review on in vitro digestion of infant formula Food Research International. ,vol. 76, pp. 373- 386 ,(2015) , 10.1016/J.FOODRES.2015.07.016
Malcolm F Fuller, Daniel Tomé, In vivo determination of amino acid bioavailability in humans and model animals. Journal of AOAC International. ,vol. 88, pp. 923- 934 ,(2005) , 10.1093/JAOAC/88.3.923
Jayne V. Woodside, Berthold V. Koletzko, Chris C. Patterson, Robert W. Welch, Scientific standards for human intervention trials evaluating health benefits of foods, and their application to infants, children and adolescents. World review of nutrition and dietetics. ,vol. 108, pp. 18- 31 ,(2013) , 10.1159/000351481
Miriam Verwei, Andreas P. Freidig, Robert Havenaar, John P. Groten, Predicted serum folate concentrations based on in vitro studies and kinetic modeling are consistent with measured folate concentrations in humans Journal of Nutrition. ,vol. 136, pp. 3074- 3078 ,(2006) , 10.1093/JN/136.12.3074
Miriam Verwei, Karin Arkbåge, Robert Havenaar, Henk van den Berg, Cornelia Witthöft, Gertjan Schaafsma, Folic Acid and 5-Methyltetrahydrofolate in Fortified Milk Are Bioaccessible as Determined in a Dynamic In Vitro Gastrointestinal Model Journal of Nutrition. ,vol. 133, pp. 2377- 2383 ,(2003) , 10.1093/JN/133.7.2377
M. M. Swindle, A. C. Smith, J. A. Goodrich, Chronic Cannulation and Fistulization Procedures in Swine: A Review and Recommendations Journal of Investigative Surgery. ,vol. 11, pp. 7- 20 ,(1998) , 10.3109/08941939809032176
Angela M. Rowan, P. J. Moughan, M. N. Wilson, K. Maher, C. Tasman-Jones, Comparison of the ileal and faecal digestibility of dietary amino acids in adult humans and evaluation of the pig as a model animal for digestion studies in man. British Journal of Nutrition. ,vol. 71, pp. 29- 42 ,(1994) , 10.1079/BJN19940108
F.J.O. Varum, G.B. Hatton, A.W. Basit, Food, physiology and drug delivery International Journal of Pharmaceutics. ,vol. 457, pp. 446- 460 ,(2013) , 10.1016/J.IJPHARM.2013.04.034
Rachel Gervais, Fleur Gagnon, Ehab E. Kheadr, Marie-Rose Van Calsteren, Edward R. Farnworth, Ismaïl Fliss, P. Yvan Chouinard, Bioaccessibility of fatty acids from conjugated linoleic acid-enriched milk and milk emulsions studied in a dynamic in vitro gastrointestinal model International Dairy Journal. ,vol. 19, pp. 574- 581 ,(2009) , 10.1016/J.IDAIRYJ.2009.05.001