Both medial prefrontal and amygdala central nucleus lesions abolish heart rate classical conditioning, but only prefrontal lesions impair reversal of eyeblink differential conditioning

作者: D.A. Powell , Mark Chachich

DOI: 10.1016/S0304-3940(98)00832-5

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摘要: Rabbits with lesions of either medial prefrontal cortex (mPFC) or amygdala central nucleus (ACN) were compared sham-lesioned animals during differential and reversal classical conditioning the eyeblink (EB) heart rate (HR) response. Lesions mPFC, but not ACN, produced a severe impairment in EB conditioning, neither lesion affected original discrimination. However, both mPFC ACN attenuation accompanying HR decelerations initial differentiation reversal. These results suggest that processing Pavlovian contingencies affects only autonomic component learning preservative somatomotor as well, whereas component.

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