Point -of -care sensors for diabetes and myocardial ischemia

摘要: Cardiovascular disease is the leading cause of death in United States, and over 20 million people this country currently have diabetes. We developed new analytical methods that potential to improve monitoring detection these diseases. Our work enables point-of-care sensing for biochemical markers diseases, advancing non-invasive diabetes rapid myocardial ischemia. Close blood glucose concentration critical management A recent approach measure tear fluid. However, relationship between poorly understood. an method determining concentration, used it help better define correlation both fasting non-fasting human subjects. also reviewed literature from last 80 years, our explain some discrepancies reported. This will aid developing contact lens-based sensors glucose, may decrease or eliminate finger-stick testing.The definitive ischemia difficult. While patients are sent home with undetected heart attack, many unnecessarily admitted hospital, costing medical system ~$12 billion a year. The Cobalt Binding Assay test has shown promise ruling out However limited by need access central clinical chemistry laboratory. Polymerized Crystalline Colloidal Array (PCCA) sensor could be at bedside rapidly detect uses photonic crystal hydrogel technology actuate color change response metal cation binding affinity changes indicative Specifically, monitor plasma metals such as Ni2+ Co2+, which been correlate improved fabricating testing PCCA applicable implementing wide variety analytes.