Expression and Distribution of Dopamine Transporter in Cardiac Tissues of the Guinea Pig
作者： Alejandro Reynoso Palomar , Berenice Navarrete Larios , Victoria Chagoya De Sánchez , Lidia Martínez Pérez , Fidel De La Cruz López
DOI: 10.1007/S11064-010-0344-7
关键词:
摘要: Dopamine transporter (DAT) is a membrane protein that it marker for dopaminergic neurons. In the present work, throught Western blot and autoradiographic studies with selective ligand DAT ([3H] WIN-35428) noradrenaline (NET) Nisoxetine), we search expression distribution of in comparison NET, cardiac tissue guinea pig order to support presence nerve cells into heart. Expression DAT, NET were evidenced by bands 75 54 kDa, respectively Binding found four chambers. However, show heterogeneous binding right atria both ventricles, whereas homogenous The results tissues different compared being an evidence
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