Monoamine- and Histamine-Synthesizing Enzymes and Neurotransmitters Within Neurons of Adult Human Cardiac Ganglia
作者： Sanjay Singh , Patricia I. Johnson , Adil Javed , Thackery S. Gray , Vassyl A. Lonchyna
关键词: Endocrinology 、 Serotonin 、 Neuropeptide 、 Neurotransmitter 、 Monoamine neurotransmitter 、 Neurochemistry 、 Neurotransmission 、 Neuron 、 Dopamine 、 Biology 、 Internal medicine
摘要: Background—Cardiac ganglia were originally thought to contain only cholinergic neurons relaying parasympathetic information from preganglionic brain stem the heart. Accumulating evidence, however, suggests that cardiac a heterogeneous population of synthesize or respond several different neurotransmitters and neuropeptides. Reports regarding monoamine histamine synthesis neurotransmission within ganglia, present conflicting are limited in number. Furthermore, very few studies have examined neurochemistry adult human ganglia. The purpose this study was, therefore, determine whether monoamine- histamine-synthesizing enzymes exist Methods Results—Human heart tissue containing was obtained during autopsies patients without cardiovascular pathology. Avidin-biotin complex immunohistochemistry used demonstrat...
sci-hub.se 参考文章(46)
J Gu, J M Polak, J M Allen, W M Huang, M N Sheppard, K Tatemoto, S R Bloom, High Concentrations of a Novel Peptide, Neuropeptide Y, in the Innervation of Mouse and Rat Heart' Journal of Histochemistry and Cytochemistry. ,vol. 32, pp. 467- 472 ,(1984) , 10.1177/32.5.6546942
Roberto Levi, J.Olatunde Kuye, Pharmacological characterization of cardiac histamine receptors: sensitivity to H1-receptor antagonists. European Journal of Pharmacology. ,vol. 27, pp. 330- 338 ,(1974) , 10.1016/0014-2999(74)90008-9
LOUIS TSUN CHEUNG CHOW, WING HING CHOW, JOSEPH C. K. LEE, SHARRON SAU MING CHOW, ROBERT H. ANDERSON, JOHN A. GOSLING, Postmortem changes in the immunohistochemical demonstration of nerves in human ventricular myocardium. Journal of Anatomy. ,vol. 192, pp. 73- 80 ,(1998) , 10.1046/J.1469-7580.1998.19210073.X
James A. Arrowood, Anthony J. Minisi, Evelyne Goudreau, Annette B. Davis, Anne L. King, Absence of Parasympathetic Control of Heart Rate After Human Orthotopic Cardiac Transplantation Circulation. ,vol. 96, pp. 3492- 3498 ,(1997) , 10.1161/01.CIR.96.10.3492
DM O'Malley, JH Sandell, RH Masland, Co-release of acetylcholine and GABA by the starburst amacrine cells The Journal of Neuroscience. ,vol. 12, pp. 1394- 1408 ,(1992) , 10.1523/JNEUROSCI.12-04-01394.1992
J Wharton, J M Polak, L Gordon, N R Banner, D R Springall, M Rose, A Khagani, J Wallwork, M H Yacoub, Immunohistochemical demonstration of human cardiac innervation before and after transplantation. Circulation Research. ,vol. 66, pp. 900- 912 ,(1990) , 10.1161/01.RES.66.4.900
Murray Esler, Graeme Eisenhofer, Anthony Dart, Jaye Chin, Helen Cox, Gavin Lambert, Garry Jennings, Adrenaline release by the human heart. Clinical and Experimental Pharmacology and Physiology. ,vol. 18, pp. 67- 70 ,(1991) , 10.1111/J.1440-1681.1991.TB01408.X
J. A. Armour, Histamine-sensitive intrinsic cardiac and intrathoracic extracardiac neurons influence cardiodynamics American Journal of Physiology-regulatory Integrative and Comparative Physiology. ,vol. 270, ,(1996) , 10.1152/AJPREGU.1996.270.4.R906
David Jacobowitz, HISTOCHEMICAL STUDIES OF THE RELATIONSHIP OF CHROMAFFIN CELLS AND ADRENERGIC NERVE FIBERS TO THE CARDIAC GANGLIA OF SEVERAL SPECIES Journal of Pharmacology and Experimental Therapeutics. ,vol. 158, pp. 227- 240 ,(1967)
Armour Ja, Intrinsic cardiac neurons involved in cardiac regulation possess alpha 1-, alpha 2-, beta 1- and beta 2-adrenoceptors. Canadian Journal of Cardiology. ,vol. 13, pp. 277- 284 ,(1997)