Acute Effects of the Novel Psychoactive Drug 2C-B on Emotions.

摘要: Background. 2C-B (Nexus) is one of the most widespread novel psychoactive substances. There limited information about its pharmacological properties, and few studies in humans concern acute chronic effects. has been classified as a stimulant, hallucinogen, entactogen, and/or empathogen. Objectives. To evaluate emotional, subjective, cardiovascular effects 2C-B. Methods. Twenty healthy recreational users (12 women) self-administered 20 mg dose Evaluations included emotional (IAPS, FERT, speech), subjective (visual analog scales, ARCI, VESSPA, HRS, POMS questionnaires), (blood pressure heart rate). Results. Positive predominated with reduction anger under influence It did, however, increase reactivity to negative stimuli decrease ability recognize expressions happiness. Augmented emotionality speech could be appreciated by others. induced euphoria well-being, changes perceptions, slight hallucinogenic states. Mild sympathetic actions were observed. Conclusions. The specific profile that exerts on emotions suggests classification an entactogen psychedelic properties.