作者: Kimiyasu Takoh
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摘要: A method for detecting a target substance, provided by the present invention, is characterized in that comprising steps of: preparing complex (hybrid) an aptamer which binds to first nucleic acid fragment nucleotide sequence complementary and photoisomerizable molecule bound portion of sequence, wherein with form double-stranded nucleotides binding; subjecting photoisomerization treatment destabilize binding complex; forming substance so as dissolve destabilized (hybrid); second restabilize dissolution separates from aptamer.