Exhaled nitric oxide is increased in active fibrosing alveolitis.
作者： Paolo Paredi , S.A. Kharitonov , S. Loukides , P. Pantelidis , R. M. du Bois
关键词:
摘要: Study objectives Interstitial inflammation is a major aggravating factor in fibrosing lung disease associated with scleroderma (FASSc) and cryptogenic alveolitis (CFA). Exhaled nitric oxide (NO) production increased asthma bronchiectasis reflects the degree of inflammation. We investigated whether measuring levels exhaled NO valuable assessing activity patients CFA FASSc. Measurements results were measured 11 (mean age ± SEM, 58 12 years old; 5 male) 17 FASSc age, 48 9 male), they compared to BAL cell counts function. Patients had elevated (11.2 1.0 parts per billion [ppb] 9.8 ppb, respectively; p > 0.05), whereas group 13 nonsmoking normal subjects, not (6.9 0.5 ppb; 14%, neutrophils 4%, or eosinophils 3%) significantly higher (13.2 1.8 ppb), neutrophil (16.5 4.0%) lymphocyte (26.8 3.4%) than did who inactive (6.7 1.2 1.3 1.0% 7.5 1.3%, Conclusions conclude that may be useful addition monitoring.
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