Application of 2-trichloromethylbenzimidazole in analytical chemistry: a highly selective chromogenic reagent for thin-layer chromatography and some other analytical uses.

摘要: 2-Trichloromethylbenzimidazole (TCMB) was used as a chromogenic reagent in organic or inorganic analysis, mainly thin-layer chromatography (TLC). In reactions of TCMB with some heteroaromatic nitrogen containing compounds, such azines, azoles and benzazoles, formation high colored products occurred. For the reaction highly regioselective, since both adjacent α-positions versus atom(s) must not be substituted. A TLC method detection developed. Thirty azoles, benzazoles were detected at limit 10 ng to 1 μg. This also applied for pesticides, attempts construct active passive dosimeters nicotine made. prechromatographic aromatic o-diamines methyl trichloroacetimidate, its derivatives formed situ. Followed by visualization pyridine vapors, this procedure o-phenylenediamine derivatives. The product (LI Complex) identified fully characterized. Two different mechanisms: electron deficient basic like pyridine, more acidic example, pyrrole, discussed. aqueous solutions, LI Complex may new indicator complexometric, adsorption acid-base titration compounds.