Hardy-Weinberg Testing for Continuous Data

摘要: Estimation of allelic and genotypic distributions for continuous data using kernel density estimation is discussed illustrated some variable number tandem repeat data. These estimates provide a useful representation when only the many variants at locus are present in sample. Two Hardy-Weinberg test procedures introduced data: chi-square with statistic TCCS based on Hellinger's distance . Simulations used to compare powers these tests each other intraclass correlation TIC , as well power Fisher's exact TFET applied discretized Results indicate that better than THD but neither powerful The does not perform examined this article.