Uso de plasma rico en factores de crecimiento (PRFC) en combinación con biomateriales como coadyuvantes en la regeneración periodontal en defectos intraóseos

摘要: Objective: To evaluate the efficacy of periodontal regeneration in combination with biomaterials CFRP bone treating intrabony defects. Introduction: Periodontal disease results destruction tissues supporting teeth. The ultimate goal therapy is to stop progression and regenerate lost tissue, forming a new cementum, ligament, i.e., regeneration. In field tissue are 3 requirements get best result: scaffold, cell regulators. response these points allow use bioactive agents such as CFRP. consists small volume very specific preparation plateletrich plasma whose activation allows biocompatible three-dimensional matrix fibrin from which release gradually set proteins growth factors that help speed both healing An important point consider factor means time these. biomaterial can fill this role during process while roles depending on same. Methodology: We present an experimental study, analytical, longitudinal, prospective open. Which was held at Graduate Periodontics, Faculty Dentistry Autonomous University Tamaulipas, selecting 16 defects, where open curettage were performed placement according group assigned, each four defects: Group A, CFRP, B, graft, allograft C D alloplastic, alloplastic Previous periapical radiographic study. protocol obtain fraction is. Postoperative assessments immediately, 7, 15 60 days. And biopsy days 12 months for histology. Results: relation clinical, histological findings indicate postoperative stimulation all groups regeneration, presenting ideal conditions Discussion: Bone considered items have various functions as: scaffolding, endogenous exogenous adhesion, through transport agents, maintaining anatomical characteristics preventing invagination adjacent physical barrier space required cellular repopulation. Conclusion: technical regenerative offer alternative suitable quality fabrics. histologic satisfactory latest evidence surgical treatment aims achieve