Growth Curve of an Experimental Solid Tumor Following Radiotherapy

作者: Larry Norton , Richard Simon

DOI: 10.1093/JNCI/58.6.1735

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摘要: Because it has long been recognized that the growth of most untreated tumors is well described by Gompertzian or exponential curves but treated never characterized mathematically, we developed and applied an equation that, while not dependent on restrictive assumptions unmeasurable variables, was nevertheless capable describing perturbed as unperturbed growth. For 3964A rat hepatoma, a functional relationship between dose level radiotherapy growth-curve response derived used for predictive purposes. An implied tumor size sensitivity to therapy some clinical implications were examined.

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