作者: Charlotte k. Ryan , Gregory D. Potter
DOI: 10.1097/00004836-199507000-00002
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摘要: Commercially available endoscope disinfecting solutions readily cause colonic damage if allowed to contact mucosa. The two most common cleaning differ in their initial toxic effect (glutaraldehyde directly injuries crypt epithelium, and hydrogen peroxide compromises mucosal stroma), but both ultimately result tissue necrosis over time. Within 12-48 h after colonoscopy, patients show signs of bloody diarrhea, cramping, fever--symptoms that may be confused with an infectious process. Based on a literature review our own experimental studies, we conclude alone is responsible for unique form colitis commonly referred as pseudolipomatosis by pathologists. This controversial lesion becomes visible opaque plaques or pseudomembranes even while colonoscopy progress almost assuredly due the effervescent release molecular oxygen. Diligent rinsing necessary minimize patients' exposure residual chemicals endoscope. When automatic machine employed, it require strict adherence proper maintenance volume adjustments rinse cycle. Forced air drying additional preprocedure channels exterior scope should ensure chemical-free examination.