Treating hepatitis C virus in HIV patients: are side effects a real obstacle?

作者: Massimo Puoti , Paola Nasta , Alessandro Matti , Giampiero Carosi , Francesca Gatti

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摘要: Hepatitis C virus-related long-term complications are nowadays a leading cause of morbidity and mortality in HIV-infected persons. According to international guidelines, all HIV/HCV-coinfected patients should be evaluated and, if eligible, treated with pegylated interferon plus ribavirin. The management anti-HCV treatment side effects, which may even more serious HIV patients, is very important minimize early discontinuations. purpose this review supply clinicians an update, provided by the most recent relevant literature, underlying mechanisms, incidence, advice about ribavirin effects HCV/HIV-coinfected patients.

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