Novel influenza A (H1N1): clinical features of pediatric hospitalizations in two successive waves

摘要: Summary Objective To describe and compare the characteristics of children hospitalized with novel influenza A (H1N1) during two successive waves. Methods This was a medical chart review all in French Canadian pediatric hospital Montreal spring fall 2009 positive real-time polymerase chain reaction for flu-like symptoms. Results We included 202 median age 4.9 (range 0.1–18) years. Demographic clinical features waves were similar. One or more underlying conditions found 59% children. Clinical findings at admission were: fever (98%), cough (88%), congestion/rhinorrhea (58%), gastrointestinal symptoms (47%), oxygen saturation below 95% (33%), sore throat (20%), neurological (9%). Admission to intensive care unit required 22 (11%) children, 14 patients needed respiratory support. During second wave, duration stay shorter (3 vs. 4 days, p =0.003) oseltamivir used often (84% 40%, Conclusions Children H1N1 mainly school-aged suffered from moderate disease. Although severity disease similar, prescribed frequently length wave.