Alterations in antioxidant defense system of workers chronically exposed to arsenic, cadmium and mercury from coal flying ash.

摘要: Humans are exposed to different stress factors that responsible for over-production of reactive oxygen species. Exposure heavy metals is one these factors. The aim the study was analyze effect chronic exposure through coal flying ash on efficiency antioxidative defensive mechanisms, represented by activity superoxide dismutase, glutathione peroxidase and ascorbic acid. Nonessential elements such as arsenic mercury levels showed a significant increase (p > 0.001) in power plant workers rather than control subjects. There were no differences blood cadmium between We found positive correlation (p < 0.05) BAs/SZn (r = 0.211), BAs/BSe (r = 0.287), BCd/SCu (r = 0.32) BHg/BSe (r = 0.263) workers. Red cell antioxidant enzymes plasma acid significantly lower plants group (p < 0.002). can conclude mercury, blood, despite their concentration within reference values, affect concentration, dismutase activity, which able risk oxidative stress.