Kinetics and Mechanism of the Pyridinolysis of Diisopropyl Thiophosphinic Chloride in Acetonitrile

摘要: = 0.80-0.96). The anilinolyses often P=S systems in MeCN are reviewed on the basis of DKIEs and selectivity parameters to obtain systematicinformation mechanism for thiophosphoryl transfer reactions. steric effects twoligands reactivity, DKIEs, mechanism, substituent nucleophile (X) arediscussed.Key Words : Phosphoryl reaction, Anilinolysis, Diisopropyl thiophosphinic chloride, Deuterium ki-netic isotope effect IntroductionA considerable amount work has been focused thetwo types phosphoryl reac-tion mechanisms; stepwise through a trigonal bipyramidalpentacoordinate (TBP-5C) intermediate, concertedthrough single pentacoordinate transition state (TS). Theattacking direction can be backside and/orfrontside, depending substrate, nucleophile, leavinggroup, reaction condition. In previous work, this labreported upon various thiopho-sphoryl reactions: anilinolysis,