The Atrial Natriuretic Peptide in Human Hypertension

作者: J. Genest , P. Larochelle , J. R. Cusson , M. Cantin

DOI: 10.1007/978-3-642-83858-3_11

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摘要: Measurements by radioimmunoassay of the ANP C-terminal (Ser 99-Tyr 126), N-terminal (Asn 1-Arg 98), and cyclic GMP in plasma 77 healthy subjects 32 patients with labile hypertension but diastolic pressures below 90 mmHg at time blood sampling, 74 mild between 90–104 mmHg, 16 moderate 105 114 7 severe above 115 were found to be within normal range all groups untreated essential hypertension. In view reported increases right left atrial hypertension, these findings suggest a hyporesponsiveness atria release

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