Recognition of lipids from pollens by CD1-restricted T cells.
作者： Fabrizio Spinozzi , Steven A. Porcelli
DOI: 10.1016/J.IAC.2006.11.004
关键词:
摘要: Allergic rhinitis and asthma should be considered as organ-specific inflammatory diseases in which the genetic background has determined a local overproduction of Th2-type cytokines an overexpansion particular APCs T cells. Among latter, potential pathogenetic role could assumed for natural killer cells, expressing both invariant (Vα24/Vβ11) classic αβ or γδ T-cell receptors. Recent studies support this notion also suggest that surface pollen substances nonprotein structure, such lipid components recognized by CD1, viewed one foreign materials against immune system allergic subject can mount response.
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