Exercise-intensity dependent alterations in plasma redox status do not reflect skeletal muscle redox-sensitive protein signaling.

摘要: Abstract Objectives Redox homeostasis and redox-sensitive protein signaling play a role in exercise-induced adaptation. The effects of sprint-interval exercise (SIE), high-intensity interval (HIIE) continuous moderate-intensity (CMIE), on post-exercise plasma redox status are unclear. Furthermore, whether reflects skeletal muscle is unknown. Design In randomized crossover design, eight healthy adults performed cycling session HIIE (5 × 4 min at 75% W max ), SIE (4 × 30 s Wingate’s), CMIE work-matched to (30 min 50% ). Methods Plasma hydrogen peroxide (H 2 O thiobarbituric acid reactive substances (TBARS), superoxide dismutase (SOD) activity, catalase activity were measured immediately post, 1 h, 2 h 3 h post-exercise. biomarkers correlated with phosphorylation p38-MAPK, JNK, NF-κB, IκBα content Results was greater (56.6 ± 3.8 U ml −1 ) compared (42.7 ± 3.2, p  significantly (p   0.05). Conclusions Low-volume elicited CMIE, H CMIE. did not, however, adequately reflect signaling.