Endothelial Dysfunction Induced by Post-Prandial Lipemia: Complete Protection Afforded by High-Intensity Aerobic Interval Exercise
作者： Gjertrud Aunet Tyldum , Inga Ekeberg Schjerve , Arnt Erik Tjønna , Idar Kirkeby-Garstad , Tomas O. Stølen
DOI: 10.1016/J.JACC.2008.09.033
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摘要: Objectives This study was designed to the effect of exercise and a high-fat meal (HFM) on endothelial function. Background Post-prandial lipemia oppose each other in terms cardiovascular risk; however, mechanism their interaction is not well understood. Methods Endothelial function assessed by brachial artery flow-mediated dilation (FMD) 8 healthy men before after an HFM preceded (16 18 h) rest, single bout continuous moderate-intensity (CME), high-intensity interval (HIIE). Results Before HFM, initial diameters were similar all trials (0.43 ± 0.04 cm), but basal diameter decreased only control (0.39 0.03 cm) CME (0.38 trials. FMD/shear improved (+20%, p Conclusions These findings reveal clinically relevant protective acute vasculature that clearly intensity dependent tightly related exercise-induced antioxidant capacity. (Endothelial Dysfunction Induced Postprandial Lipemia; NCT00660491 )
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