Physiological consequences of the work of breathing and of inspiratory muscle training

摘要: A reduced blood lactate concentration ([lac-]B) is commonly observed during whole-body exercise following inspiratory muscle training (IMT). However, whether the muscles are, in part, source of these reductions remains unknown. Accordingly, this thesis investigated: (I) contribution respiratory to systemic [lac-]B and (II) effects IMT upon exchange clearance. In addition, also evaluated determinants strength (maximal mouth pressure; MIP). All subjects were healthy, active free pulmonary disease. Under resting conditions, 10 min intense volitional hyperpnoea at 85% maximal minute ventilation (VE max) increased by 0.96 mmol.L-1. This was attenuated 25% 6 wks IMT. 8 90% VE max imposed steady state (MLSS) 0.99 Following wk IMT, hyperpnoea-mediated increase lower 26%, respectively. Relative pre-IMT, loading trained using a low-intensity pressure threshold resistance (15 cmH2O) immediately accelerated both clearance capacities ~70%.