The major histocompatibility complex and the chemosensory recognition of individuality in rats.
作者： Richard E. Brown , Prim B. Singh , Bruce Roser
DOI: 10.1016/0031-9384(87)90186-7
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摘要: The present experiments provide the first evidence that congenic strains of rats, which differ only in MHC, produce discriminably different urinary chemosignals. Urine from adult male PVG and PVG.R1 A region (class 1) was used a habituation-dishabituation task, with PVG-RT1u, Wistar albino, Lister hooded rats as subjects. males easily distinguished by all three strains. Individual were not their urine odours, but individual appeared to have odours. repetition this experiment indicated discrimination may been due impurities urine. Odours serum sufficient for between two strains, nor class 1 molecule purified removed (remainder fraction) could, however, be distinguish chemicals give distinctive odour fragments or small molecules associated molecule. MHC appears control cues are mammals recognition an olfactory basis kin mechanism controls these signals is unknown.
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elsevier.com参考文章(31)
Kunio Yamazaki, Masashi Yamaguchi, Edward A. Boyse, Lewis Thomas, The Major Histocompatibility Complex as a Source of Odors Imparting Individuality among Mice Chemical Signals. pp. 267- 273 ,(1980) , 10.1007/978-1-4684-1027-3_17
Zuleyma Tang Halpin, Individual Odors among Mammals: Origins and Functions Advances in The Study of Behavior. ,vol. 16, pp. 39- 70 ,(1986) , 10.1016/S0065-3454(08)60187-4
P. Parham, Purification of immunologically active HLA-A and -B antigens by a series of monoclonal antibody columns. Journal of Biological Chemistry. ,vol. 254, pp. 8709- 8712 ,(1979) , 10.1016/S0021-9258(19)86749-2
Gary K. Beauchamp, Avery N. Gilbert, Lewis Thomas, Kunio Yamazaki, Olfactory discrimination of mouse strains (Mus musculus) and major histocompatibility types by humans (Homo sapiens). Journal of Comparative Psychology. ,vol. 100, pp. 262- 265 ,(1986) , 10.1037//0735-7036.100.3.262
Barbara Gregg, Del D. Thiessen, A simple method of olfactory discrimination of urines for the Mongolian gerbil, Meriones unguiculatus Physiology & Behavior. ,vol. 26, pp. 1133- 1136 ,(1981) , 10.1016/0031-9384(81)90221-3
F. J. Schwende, J. W. Jorgenson, M. Novotny, Possible chemical basis for histocompatibility-related mating preference in mice Journal of Chemical Ecology. ,vol. 10, pp. 1603- 1615 ,(1984) , 10.1007/BF00988428
P. W. Andrews, E. A. Boyse, Mapping of an h-2 linked gene that influences mating preference in mice. Immunogenetics. ,vol. 6, pp. 265- 268 ,(1978) , 10.1007/BF01563917
K Yamazaki, G. Beauchamp, C. Wysocki, J Bard, L Thomas, E. Boyse, Recognition of H-2 types in relation to the blocking of pregnancy in mice Science. ,vol. 221, pp. 186- 188 ,(1983) , 10.1126/SCIENCE.6857281
PETER G. HEPPER, Kin recognition: functions and mechanisms. A review. Biological Reviews. ,vol. 61, pp. 63- 93 ,(1986) , 10.1111/J.1469-185X.1986.TB00427.X
Prim B. Singh, Richard E. Brown, Bruce Roser, MHC antigens in urine as olfactory recognition cues Nature. ,vol. 327, pp. 161- 164 ,(1987) , 10.1038/327161A0