Use of interfering rna for treating an hiv infection
作者： Anne-Geneviève Marcelin , Vincent Calvez
DOI:
关键词:
摘要: The present invention relates to interfering RNAs, in particular miRNAs, capable of specifically blocking the replication a strain HIV virus that is resistant an antiretroviral compound, and use thereof for treating infections by this type virus.
lens.org 参考文章(16)
Vinod Scaria, Samir Kumar Brahmachari, Beena Pillai, Manoj Hariharan, Human microrna targets in hiv genome and a method of identification thereof ,(2006)
Jonathan M. Schapiro, Robert W. Shafer, HIV-1 drug resistance mutations: an updated framework for the second decade of HAART. Aids Reviews. ,vol. 10, pp. 67- 84 ,(2008)
Tanya Sandrock, Robert Craigie, Inhibitors of viral integrase and methods of use ,(2010)
Abhijit Chaudhuri, John Gow, Materials and methods for diagnosis and treatment of chronic fatigue syndrome ,(2006)
Neeranat Thienthong, Giang Thanh Le, Lisa Jane Winfield, Eric Dale Jones, David Ian Rhodes, De Graff Nicholas Andrew Van, John Joseph Deadman, Compounds having antiviral properties ,(2009)
Peter M. Huelsmann, Pia Rauch, Kristina Allers, Matthias J. John, Karin J. Metzner, Inhibition of drug-resistant HIV-1 by RNA interference. Antiviral Research. ,vol. 69, pp. 1- 8 ,(2006) , 10.1016/J.ANTIVIRAL.2005.10.001
Karin Jasmijn von Eije, Olivier ter Brake, Ben Berkhout, Human Immunodeficiency Virus Type 1 Escape Is Restricted When Conserved Genome Sequences Are Targeted by RNA Interference Journal of Virology. ,vol. 82, pp. 2895- 2903 ,(2008) , 10.1128/JVI.02035-07
S. Sulic, Inactivation of S6 ribosomal protein gene in T lymphocytes activates a p53-dependent checkpoint response Genes & Development. ,vol. 19, pp. 3070- 3082 ,(2005) , 10.1101/GAD.359305
Tom Maniatis, Joseph Sambrook, E. F. Fritsch, Molecular Cloning: A Laboratory Manual ,(2001)
Hironori Nishitsuji, Michinori Kohara, Mari Kannagi, Takao Masuda, Effective Suppression of Human Immunodeficiency Virus Type 1 through a Combination of Short- or Long-Hairpin RNAs Targeting Essential Sequences for Retroviral Integration Journal of Virology. ,vol. 80, pp. 7658- 7666 ,(2006) , 10.1128/JVI.00078-06