Materials and methods for diagnosis and treatment of chronic fatigue syndrome

作者: Abhijit Chaudhuri , John Gow

DOI:

关键词: Human leukocyte antigenKinaseMedicineLesionDefensinProstaglandin D2 synthaseCXCR4ImmunologyChronic fatigue syndromeEncephalitis

摘要: The invention relates to materials and methods for diagnosis treatment of chronic fatigue syndrome/myalgic encephalitis. A number genes are identified which expressed at abnormal levels in patients affected by CFS/ME as compared normal healthy individuals. These include those encoding defensin α1, haemoglobin γ, CXCR4, tubulin beta 1, serine/threonine kinase 17B, HLA DRss4 prostaglandin D2 synthase. provide objective disease markers that may be used diagnostic tests support the or monitoring effectiveness therapy. They also a rational basis classifying according biochemical lesion underlying their symptoms enable provision appropriate targeted therapies.

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