作者: Abhijit Chaudhuri , John Gow
DOI:
关键词: Human leukocyte antigen 、 Kinase 、 Medicine 、 Lesion 、 Defensin 、 Prostaglandin D2 synthase 、 CXCR4 、 Immunology 、 Chronic fatigue syndrome 、 Encephalitis
摘要: The invention relates to materials and methods for diagnosis treatment of chronic fatigue syndrome/myalgic encephalitis. A number genes are identified which expressed at abnormal levels in patients affected by CFS/ME as compared normal healthy individuals. These include those encoding defensin α1, haemoglobin γ, CXCR4, tubulin beta 1, serine/threonine kinase 17B, HLA DRss4 prostaglandin D2 synthase. provide objective disease markers that may be used diagnostic tests support the or monitoring effectiveness therapy. They also a rational basis classifying according biochemical lesion underlying their symptoms enable provision appropriate targeted therapies.