Neurotrophic action of 5-hydroxylated polymethoxyflavones: 5-demethylnobiletin and gardenin A stimulate neuritogenesis in PC12 cells.
作者： Szu-Ping Chiu , Ming-Jiuan Wu , Pei-Yi Chen , Yi-Ru Ho , Mi-Hsueh Tai
DOI: 10.1021/JF4024678
关键词:
摘要: Polymethoxyflavones (PMFs) exhibit a broad spectrum of biological properties, including anticancer, antiatherogenic, and neuroprotective effects. The aim this study is to investigate the neurotr...
acs.org
core.ac.uk 
sci-hub.se 参考文章(35)
Lloyd A. Greene, John M. Aletta, Adriana Rukenstein, Steven H. Green, [18] PC12 pheochromocytoma cells: culture, nerve growth factor treatment, and experimental exploitation Peptide Growth Factors - Part B. ,vol. 147, pp. 207- 216 ,(1987) , 10.1016/0076-6879(87)47111-5
L. Reznichenko, T. Amit, M. B. H. Youdim, S. Mandel, Green tea polyphenol (-)-epigallocatechin-3-gallate induces neurorescue of long-term serum-deprived PC12 cells and promotes neurite outgrowth. Journal of Neurochemistry. ,vol. 93, pp. 1157- 1167 ,(2005) , 10.1111/J.1471-4159.2005.03085.X
Valerie Boss, John D. Roback, Andrew N. Young, Linda J. Roback, Daniela M. Vogt Weisenhorn, Rafael Medina-Flores, Bruce H. Wainer, Nerve Growth Factor, But Not Epidermal Growth Factor, Increases Fra-2 Expression and Alters Fra-2/JunD Binding to AP-1 and CREB Binding Elements in Pheochromocytoma (PC12) Cells The Journal of Neuroscience. ,vol. 21, pp. 18- 26 ,(2001) , 10.1523/JNEUROSCI.21-01-00018.2001
O. V. Vitolo, A. Sant'Angelo, V. Costanzo, F. Battaglia, O. Arancio, M. Shelanski, Amyloid β-peptide inhibition of the PKA/CREB pathway and long-term potentiation: Reversibility by drugs that enhance cAMP signaling Proceedings of the National Academy of Sciences of the United States of America. ,vol. 99, pp. 13217- 13221 ,(2002) , 10.1073/PNAS.172504199
L. A. Greene, A. S. Tischler, Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 73, pp. 2424- 2428 ,(1976) , 10.1073/PNAS.73.7.2424
K Das, Assessment of PC12 cell differentiation and neurite growth: a comparison of morphological and neurochemical measures Neurotoxicology and Teratology. ,vol. 26, pp. 397- 406 ,(2004) , 10.1016/J.NTT.2004.02.006
Monika Ehrhart-Bornstein, Marek Treiman, Gert H. Hansen, Arne Schousboe, Niels A. Thorn, Aase Frandsen, Parallel expression of synaptophysin and evoked neurotransmitter release during development of cultured neurons International Journal of Developmental Neuroscience. ,vol. 9, pp. 463- 471 ,(1991) , 10.1016/0736-5748(91)90032-H
In Kei Lam, Deepa Alex, You-Hua Wang, Ping Liu, Ai-Lin Liu, Guan-Hua Du, Simon Ming Yuen Lee, In vitro and in vivo structure and activity relationship analysis of polymethoxylated flavonoids: identifying sinensetin as a novel antiangiogenesis agent. Molecular Nutrition & Food Research. ,vol. 56, pp. 945- 956 ,(2012) , 10.1002/MNFR.201100680
O. Benavente-García, J. Castillo, Update on uses and properties of citrus flavonoids: new findings in anticancer, cardiovascular, and anti-inflammatory activity. Journal of Agricultural and Food Chemistry. ,vol. 56, pp. 6185- 6205 ,(2008) , 10.1021/JF8006568
C.J Marshall, Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation Cell. ,vol. 80, pp. 179- 185 ,(1995) , 10.1016/0092-8674(95)90401-8