Localized amyloidosis of the urinary tract: Case series of nine patients

摘要: Abstract Objectives To report 9 cases of primary localized amyloidosis the urinary tract and correlate pathologic findings with clinical cystoscopic information. Methods Patients diagnosed ureters, bladder, or urethra from 1976 to 2003 were identified. Their medical records reviewed, histochemical immunoperoxidase stains performed on tissue. Results Eight bladder one renal pelvis/ureter None our showed evidence systemic amyloidosis. Of 8 patients 5 presented gross hematuria 1 irritative symptoms 2 had detected during follow-up for urothelial carcinoma. The patient flank pain hematuria. impression was malignancy in 75% cases. Most involvement treated resection; however, required total cystectomy symptom control. information, developed recurrence. assessment amyloid deposits consistent AL type all Immunoperoxidase revealed lymphoid cells vicinity be lambda-restricted 78% Conclusions Primary is a rare condition that mimics its presentation appearance diagnostic imaging. In study, represented rather than manifestations Monoclonal populations evolving chronic inflammation may source proteins.