Ewing's Bone Sarcoma, Paternal Occupational Exposure, and Other Factors

摘要: To determine risk factors for Ewing's bone sarcoma, the authors interviewed mothers of 43 patients diagnosed between January 1978 and August 1986 193 controls in San Francisco Bay Area, California, regarding medical occupational history parents other related to subjects their immediate families. Controls were selected by using random digit dial telephone methods. Adjusted relative estimates suggest that risks elevated children whose fathers engaged agricultural occupations during period from 6 months prior conception subject up time diagnosis or interview (relative (RR) = 8.8, 95% confidence interval (CI) 1.8-42.7) had exposure herbicides, pesticides, fertilizers (RR 6.1, CI 1.7-21.9, p 0.002). Prior ingestion poison an overdose medication was more common than 4.4, 1.4-13.5). These findings should be investigated larger population-based studies specific may account associations.