[Association between the myeloperoxidase gene polymorphisms and the susceptibility to prostate cancer: a case-control study in a Chinese population].

作者: G Ding , F Liu , C Feng , J Xu , Q Ding

DOI: 10.1016/J.ACUROE.2012.03.017

关键词:

摘要: Abstract Background and objectives Prostate cancer (PCa) is the most common among men in western populations. The polymorphisms of myeloperoxidase (MPO) gene have been correlated with abnormal MPO expression increased risk various types cancers. Our study aimed to evaluate association between genetic prostate cancer. Methods Genotyping was carried out by using genotyping system (MassARRAY iPLEX; Sequenom, Inc., San Diego, CA, USA) on 1,108 PCa patients 1,525 cancer-free controls a Chinese Han population. Results Although one SNP (rs8082134, P  Conclusion data showed limited SNPs susceptibility population possible rs8082134 need further clarification.

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