Relationship of Normal CDF1 Mouse Leukocyte Kinetics to Growth Characteristics of Leukemia L1210

摘要: Leukocyte kinetics were studied in the CDF1 mouse using liquid scintillation and radioautographic technics. Although latter method provides more detailed information, former technic is readily adaptable to experimental manipulations. The of leukocytes are different from those man. Either marrow storage transit times or generation progenitor cells shorter. Data presented this study available literature support concept. selective therapeutic advantage probably related presence nonproliferating inaccessible chemotherapy as reported literature. Knowledge both normal tumor cell essential if drug scheduling be placed on a rational basis.