Prediction of transition from cognitive impairment to senile dementia: a prospective, longitudinal study.
作者： S. Artero , M. C. Tierney , J. Touchon , K. Ritchie
DOI: 10.1034/J.1600-0447.2003.00081.X
关键词:
摘要: Objective: The purpose of this investigation was to replicate the statistical approach used in a previous (Toronto study) within French population determine best predictive model for Alzheimer's disease (AD). Method: Data from neuropsychological tests two prospective studies were entered into regression model. Results: Replication Montpellier sample produced three-test with specificity 99% and sensitivity 73%. This consisted delayed auditory verbal recall test, construction category fluency test provides probability estimates transition dementia individual cases. Conclusion: models derived these longitudinal provide an empirical basis selection definition mild cognitive impairment Alzheimer type (MCI-A). small set are suitable use general practice.
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