Segregation of molecules in lipid bilayer spreading through metal nanogates.

摘要: A new methodology for nanoscopic molecular filtering was developed using a substrate with periodic array of metallic nanogates various widths between 75 and 500 nm. self-spreading lipid bilayer employed as the transport medium. Dye-labeled molecules doped in were filtered after spreading less than few tens micrometers on nanogate array. Quantitative analysis dynamics suggests that effect originates from formation chemical potential barrier at region, which is believed to be due structural change such compression imposed gate. highly localized affects ability dye-labeled penetrate The use allows transportation without any external field an electric used electrophoresis. present...