Pancreatic islet cell development and regeneration.
作者： Anthony I. Romer , Lori Sussel
DOI: 10.1097/MED.0000000000000174
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摘要: Purpose of reviewThis review will discuss recent advances in understanding mouse and human pancreatic islet cell development, novel concepts related to β dysfunction improved approaches for replenishing cells treat diabetes.Recent findingsConsiderable knowledge about d
sci-hub.se 参考文章(134)
J. Briscoe, L. Sussel, P. Serup, D. Hartigan-O'Connor, T. M. Jessell, J. L. R. Rubenstein, J. Ericson, Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling Nature. ,vol. 398, pp. 622- 627 ,(1999) , 10.1038/19315
Jan Jensen, Erna Engholm Pedersen, Philip Galante, Jacob Hald, R. Scott Heller, Makoto Ishibashi, Ryoichiro Kageyama, Francois Guillemot, Palle Serup, Ole D. Madsen, Control of endodermal endocrine development by Hes-1. Nature Genetics. ,vol. 24, pp. 36- 44 ,(2000) , 10.1038/71657
Peng Wang, Nathalie M. Fiaschi-Taesch, Rupangi C. Vasavada, Donald K. Scott, Adolfo García-Ocaña, Andrew F. Stewart, Diabetes mellitus—advances and challenges in human β-cell proliferation Nature Reviews Endocrinology. ,vol. 11, pp. 201- 212 ,(2015) , 10.1038/NRENDO.2015.9
Dina A. Balderes, Mark A. Magnuson, Lori Sussel, Nkx2.2:Cre knock-in mouse line: A novel tool for pancreas- and CNS-specific gene deletion Genesis. ,vol. 51, pp. 844- 851 ,(2013) , 10.1002/DVG.22715
Alireza Rezania, Jennifer E. Bruin, Jean Xu, Kavitha Narayan, Jessica K. Fox, John J. O'Neil, Timothy J. Kieffer, Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo. Stem Cells. ,vol. 31, pp. 2432- 2442 ,(2013) , 10.1002/STEM.1489
Maciej T. Malecki, Ulupi S. Jhala, Anthony Antonellis, Liz Fields, Alessandro Doria, Tihamer Orban, Mohammed Saad, James H. Warram, Marc Montminy, Andrzej S. Krolewski, Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus Nature Genetics. ,vol. 23, pp. 323- 328 ,(1999) , 10.1038/15500
Martin Hrabě de Angelis, Urban Lendahl, Helena Edlund, Åsa Apelqvist, Hao Li, Lukas Sommer, Paul Beatus, David J. Anderson, Tasuku Honjo, Notch signalling controls pancreatic cell differentiation Nature. ,vol. 400, pp. 877- 881 ,(1999) , 10.1038/23716
Martin F. Offield, Patricia A. Labosky, Mark A. Magnuson, Brigid L.M. Hogan, Roland W. Stein, Christopher V.E. Wright, Michael Ray, Tom L. Jetton, PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum Development. ,vol. 122, pp. 983- 995 ,(1996) , 10.1242/DEV.122.3.983
Hao Li, Silvia Arber, Thomas M. Jessell, Helena Edlund, Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9. Nature Genetics. ,vol. 23, pp. 67- 70 ,(1999) , 10.1038/12669
Anne Grapin-Botton, Amit R Majithia, Douglas A Melton, Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes Genes & Development. ,vol. 15, pp. 444- 454 ,(2001) , 10.1101/GAD.846001