作者: N. H. Ogden , A. N. J. Casey , C. H. Lawrie , N. P. French , Z. Woldehiwet
DOI: 10.1046/J.1365-2915.2002.00362.X
关键词:
摘要: Enzyme-linked immunosorbent assay (ELISA) was used to investigate the antibody responses of control sheep, and sheep naturally exposed Ixodes ricinus Linne (Acari: Ixodidae) ticks, salivary gland extract (SGE) proteins partially fed, adult I. ricinus. Comparisons between infested by Western blot analysis suggested that variations in IgG ricinus-exposed were mostly associated with specific SGE antigens. Sheep positively related numbers ticks feeding per at time samples collected, greater during spring than autumn periods activity inversely resistance measured weights nymphal engorged on sheep. These findings suggest lose their due polarization a Th1 type response some tick antigens towards Th2 when are high, natural infestations, or seasonal conditions relative nutritional stress. Potential consequences for epidemiology tick-borne diseases discussed.