IgG responses to salivary gland extract of Ixodes ricinus ticks vary inversely with resistance in naturally exposed sheep.

作者: N. H. Ogden , A. N. J. Casey , C. H. Lawrie , N. P. French , Z. Woldehiwet

DOI: 10.1046/J.1365-2915.2002.00362.X

关键词:

摘要: Enzyme-linked immunosorbent assay (ELISA) was used to investigate the antibody responses of control sheep, and sheep naturally exposed Ixodes ricinus Linne (Acari: Ixodidae) ticks, salivary gland extract (SGE) proteins partially fed, adult I. ricinus. Comparisons between infested by Western blot analysis suggested that variations in IgG ricinus-exposed were mostly associated with specific SGE antigens. Sheep positively related numbers ticks feeding per at time samples collected, greater during spring than autumn periods activity inversely resistance measured weights nymphal engorged on sheep. These findings suggest lose their due polarization a Th1 type response some tick antigens towards Th2 when are high, natural infestations, or seasonal conditions relative nutritional stress. Potential consequences for epidemiology tick-borne diseases discussed.

参考文章(37)
B. H. Fivaz, R. A. I. Norval, J. A. Lawrence, Transmission ofTheileria parva bovis (Boleni strain) to cattle resistant to the brown ear tickRhipicephalus appendiculatus (Neumann) Tropical Animal Health and Production. ,vol. 21, pp. 129- 134 ,(1989) , 10.1007/BF02236193
Geoffrey Pollott, David Croston, Planned Sheep Production ,(1985)
Stephen K. Wikel, Host resistance to tick-borne pathogens by virtue of resistance to tick infestation Annals of Tropical Medicine and Parasitology. ,vol. 74, pp. 103- 104 ,(1980) , 10.1080/00034983.1980.11687318
John Oliver Letts King, An introduction to animal husbandry ,(1978)
George B. Schoeler, Stephen A. Manweiler, Stephen K. Wikel, Cytokine responses of C3H/HeN mice infested with Ixodes scapularis or Ixodes pacificus nymphs. Parasite Immunology. ,vol. 22, pp. 31- 40 ,(2000) , 10.1046/J.1365-3024.2000.00272.X
S. SCHORDERET, M. BROSSARD, Changes in immunity to Ixodes ricinus by rabbits infested at different levels Medical and Veterinary Entomology. ,vol. 7, pp. 186- 192 ,(1993) , 10.1111/J.1365-2915.1993.TB00673.X
J. Francis, D. A. Little, RESISTANCE OF DROUGHTMASTER CATTLE TO TICK INFESTATION AND BABESIOSIS Australian Veterinary Journal. ,vol. 40, pp. 247- 253 ,(1964) , 10.1111/J.1751-0813.1964.TB08746.X