Dermatoglyphics and abnormal palmar flexion creases as markers of early prenatal stress in children with idiopathic intellectual disability.

摘要: A number of studies have shown the importance dermatoglyphics as markers prenatal disturbance in developmental disorders unknown origin. Genetic and non-genetic factors are involved aetiology intellectual disability (ID), although cause remains up to 50% cases. The aim present study was analyse dermatoglyphic traits abnormal palmar flexion creases environmental stress children with idiopathic ID (IID) using a case-control design. Three variables, which been reported altered other congenital disorders, were considered studied sample 62 IID (IQ 70): (1) fingerprint patterns; (2) total a-b ridge count (TABRC); (3) (APFCs). More arches, simplest pattern, more radial loops, an unusual found cases comparison controls (chi23 = 9.26; P 0.02), especially marked differences boys 6.5; 0.0008). significant increase APFCs also affected (chi24 28.52; < 0.00; odds ration 3.86, 95% confidence interval 1.77-8.47). For TABRC, between failed reach conventional level significance. These findings suggest that acting early development, or mechanisms involving interaction genotype environment could be some ID.