摘要: The DNA damage response (DDR), consisting of an orchestrated network of proteins effecting repair and signalling to cell cycle arrest, to allow time to repair, is essential for cell …
Donald J Skalitzky, Joseph T Marakovits, Karen A Maegley, Anne Ekker, Xiao-Hong Yu, Zdenek Hostomsky, Stephen E Webber, Brian W Eastman, Robert Almassy, Jianke Li, Nicola J Curtin, David R Newell, A Hilary Calvert, Roger J Griffin, Bernard T Golding, None, Tricyclic Benzimidazoles as Potent Poly(ADP-ribose) Polymerase-1 InhibitorsJournal of Medicinal Chemistry. ,vol. 46, pp. 210- 213 ,(2003) , 10.1021/JM0255769