Revisiting APOLT for Metabolic Liver Disease: A new Look at an old Idea.
作者： Mettu Srinivas Reddy , Rajesh Rajalingam , Mohamed Rela
DOI: 10.1097/TP.0000000000001472
关键词:
摘要: Even though auxiliary partial orthotopic liver transplantation (APOLT) as a technique was popularized in the late 80s, its role metabolic disease remains controversial. The slow progress gene therapy research, high incidence of technical complications, and problem long term graft atrophy have been roadblocks to wider application. Better understanding reciprocal dynamics portal flow regeneration between native along with multiple refinements surgical improved outcomes this operation, making it safe alternative for patients wide range noncirrhotic diseases (NCMLD). ability perform APOLT safely has also opened up exciting indications setting NCMLD. This article reviews current status NCMLD, which novel indications, rekindled fresh interest procedure.
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