摘要: Abstract Despite of the fact that lunar environment lacks essential prerequisites for supporting life, missions offer new and promising opportunities to life sciences community. Among disciplines interest are exobiology, radiation biology, ecology human physiology. In Moon offers an ideal platform studies related understanding principles, leading origin, evolution distribution life. These include analysis samples meteorites in relatively pristine conditions, radioastronomical search other planetary systems or Search Extra-Terrestrial Intelligence (SETI), on role evolutionary processes environmental limits For provides unique laboratory with built-in sources optical as well ionising investigate biological importance various components cosmic solar radiation. Before establishing a base, precursor will provide characterisation field, determination depth dose distributions different absorbers, installation flare alert system, qualification efficiency mixed environment. One most challenging projects falls into domain establishment first time artificial ecosystem celestial body beyond Earth. From this venture, better dynamics regulating our terrestrial biosphere is expected. It also serve bioregenerative support base. The base eventually long-term presence raise problems fields physiology health care, psychology sociology. Protection guidelines living hostile have be established.