Curcumin as a wound healing agent.
作者： Dania Akbik , Maliheh Ghadiri , Wojciech Chrzanowski , Ramin Rohanizadeh
DOI: 10.1016/J.LFS.2014.08.016
关键词:
摘要: Turmeric (Curcuma longa) is a popular Indian spice that has been used for centuries in herbal medicines the treatment of variety ailments such as rheumatism, diabetic ulcers, anorexia, cough and sinusitis. Curcumin (diferuloylmethane) main curcuminoid present turmeric responsible its yellow color. shown to possess significant anti-inflammatory, anti-oxidant, anti-carcinogenic, anti-mutagenic, anti-coagulant anti-infective effects. also have wound healing properties. It acts on various stages natural process hasten healing. This review summarizes discusses recently published papers effects curcumin skin The highlighted studies provide evidence ability reduce body's response cutaneous wounds inflammation oxidation. recent literature properties provides enhance granulation tissue formation, collagen deposition, remodeling contraction. become evident optimizing topical application through altering formulation essential ensure maximum therapeutical wounds.
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sci-hub.se 参考文章(72)
Ranajit K Banerjee, Uday Bandyopadhyay, Ishita Chattopadhyay, Kaushik Biswas, Turmeric and curcumin: Biological actions and medicinal applications Current Science. ,vol. 87, pp. 44- 53 ,(2004)
Leeni Koivisto, Lari Häkkinen, Hannu Larjava, Re‐epithelialization of wounds Endodontic Topics. ,vol. 24, pp. 59- 93 ,(2011) , 10.1111/ETP.12007
Stéphanie F. Bernatchez, Vinod Menon, Joseph Stoffel, Shelley-Ann H. Walters, William E. Lindroos, Mary C. Crossland, Lisa G. Shawler, Stephen P. Crossland, Joseph V. Boykin, Nitric oxide levels in wound fluid may reflect the healing trajectory Wound Repair and Regeneration. ,vol. 21, pp. 410- 417 ,(2013) , 10.1111/WRR.12048
Anthony Hasan, Hiroshi Murata, Anna Falabella, Sofia Ochoa, Linda Zhou, Evangelos Badiavas, Vincent Falanga, Dermal fibroblasts from venous ulcers are unresponsive to the action of transforming growth factor-β 11 Journal of Dermatological Science. ,vol. 16, pp. 59- 66 ,(1997) , 10.1016/S0923-1811(97)00622-1
Umakanta Subudhi, Gagan B.N. Chainy, Expression of hepatic antioxidant genes in l-thyroxine-induced hyperthyroid rats: Regulation by vitamin E and curcumin Chemico-Biological Interactions. ,vol. 183, pp. 304- 316 ,(2010) , 10.1016/J.CBI.2009.11.004
R. Blakytny, E. Jude, The molecular biology of chronic wounds and delayed healing in diabetes. Diabetic Medicine. ,vol. 23, pp. 594- 608 ,(2006) , 10.1111/J.1464-5491.2006.01773.X
JosÉ M. MatÉs, Cristina Pérez-Gómez, Ignacio Núñez De Castro, Antioxidant enzymes and human diseases Clinical Biochemistry. ,vol. 32, pp. 595- 603 ,(1999) , 10.1016/S0009-9120(99)00075-2
Gil Topman, Feng-Huei Lin, Amit Gefen, The natural medications for wound healing - Curcumin, Aloe-Vera and Ginger - do not induce a significant effect on the migration kinematics of cultured fibroblasts. Journal of Biomechanics. ,vol. 46, pp. 170- 174 ,(2013) , 10.1016/J.JBIOMECH.2012.09.015
Ramendra K. Singh, Diwakar Rai, Dipti Yadav, A. Bhargava, J. Balzarini, E. De Clercq, Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid European Journal of Medicinal Chemistry. ,vol. 45, pp. 1078- 1086 ,(2010) , 10.1016/J.EJMECH.2009.12.002
Preetha Anand, Ajaikumar B Kunnumakkara, Robert A Newman, Bharat B Aggarwal, None, Bioavailability of curcumin: problems and promises. Molecular Pharmaceutics. ,vol. 4, pp. 807- 818 ,(2007) , 10.1021/MP700113R