A magnetic nanoparticle supported Ni2+-containing ionic liquid as an efficient nanocatalyst for the synthesis of Hantzsch 1,4-dihydropyridines in a solvent-free dry-system

摘要: The highly efficient synthesis of 1,4-dihydropyridines (1,4-DHPs) is reported via the condensation reaction aldehydes, ethyl acetoacetate and ammonium acetate, using an environmentally benign Ni2+-containing 1-methyl-3-(3-trimethoxysilylpropyl) imidazolium chloride ionic liquid on magnetic Fe3O4 nanoparticles (IL–Ni(II)–MNPs) as a new catalyst under solvent-free conditions at 70 °C. method presented here applies tenets green chemistry to generate biologically interesting products in media. key features this protocol from point view are use heterogeneous reusable catalyst, high yields products, short times. can be easily recovered mixture external magnet, reused several times without significant loss performance.