Factor VIII clotting activity
作者： P. M. Mannucci , A. Tripodi
DOI: 10.1007/978-94-011-4722-4_11
关键词:
摘要: Factor VIII activity has been historically measured with two types of methods: the one-stage assay, based on activated partial thromboplastin time (APTT) (Chapter 5) and two-stage generation test. The relative merits assays have debated1,2. In general, results obtained same samples are similar; however, discrepancies can be seen in plasmas which contain factors coagulation cascade. These make clotting times assay shorter than expected basis factor content, resulting a significant overestimation activity. For reason, is often unsuitable to determine concentrates. Even though does not seem suffer from drawback, it difficult perform because reagents employed need high degree standardization achieve less specialized clinical laboratories.
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sci-hub.st 参考文章(10)
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