Mucosa-associated lymphoid tissue lymphoma in Sjögren's syndrome: risks, management, and prognosis.

作者: Michael Voulgarelis , Haralampos M. Moutsopoulos

DOI: 10.1016/J.RDC.2008.08.006

关键词:

摘要: Sjogren's syndrome is a chronic inflammatory disease primarily affecting the exocrine glands. Its association with lymphoma well documented, salivary extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue type being most common and constituting major complication. These neoplasms are antigen-stimulated B-cell characterized by localized stage, indolent clinical course, recurrence in other sites. This article presents review literature discusses clinical, histopathologic, therapeutic, prognostic aspects these tumors syndrome. In addition, it highlights predictor markers development.

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