Clinical Significance of UDP-Glucuronosyltransferase 1A1*6 for Toxicities of Combination Chemotherapy with Irinotecan and Cisplatin in Gynecologic Cancers

作者: Masashi Takano , Masafumi Kato , Tomoyuki Yoshikawa , Naoki Sasaki , Junko Hirata

DOI: 10.1159/000209335

关键词:

摘要: Background: To investigate the effects of UDP-glucuronosyltransferase 1A1 (UGT1A1) *28, *6 and *27 in patients with gynecologic cancer who received chemotherapy irinotecan

参考文章(27)
Kimie Sai, Yoshiro Saito, Hiromi Sakamoto, Kuniaki Shirao, Koichi Kurose, Mayumi Saeki, Shogo Ozawa, Nahoko Kaniwa, Setsuo Hirohashi, Nagahiro Saijo, Jun-ichi Sawada, Teruhiko Yoshida, Importance of UDP-glucuronosyltransferase 1A1∗6 for irinotecan toxicities in Japanese cancer patients Cancer Letters. ,vol. 261, pp. 165- 171 ,(2008) , 10.1016/J.CANLET.2007.11.009
S. Adachi, T. Ogasawara, N. Yamasaki, H. Shibahara, R. Kanazawa, Y. Tsuji, T. Takemura, K. Koyama, A pilot study of CPT-11 and cisplatin for ovarian clear cell adenocarcinoma. Japanese Journal of Clinical Oncology. ,vol. 29, pp. 434- 437 ,(1999) , 10.1093/JJCO/29.9.434
J. M. Hoskins, R. M. Goldberg, P. Qu, J. G. Ibrahim, H. L. McLeod, UGT1A1*28 Genotype and Irinotecan-Induced Neutropenia: Dose Matters Journal of the National Cancer Institute. ,vol. 99, pp. 1290- 1295 ,(2007) , 10.1093/JNCI/DJM115
Elisabeth Rouits, Michèle Boisdron-Celle, Agnès Dumont, Olivier Guérin, Alain Morel, Erick Gamelin, Relevance of Different UGT1A1 Polymorphisms in Irinotecan-Induced Toxicity: A Molecular and Clinical Study of 75 Patients Clinical Cancer Research. ,vol. 10, pp. 5151- 5159 ,(2004) , 10.1158/1078-0432.CCR-03-0548
Patrick Therasse, Susan G. Arbuck, Elizabeth A. Eisenhauer, Jantien Wanders, Richard S. Kaplan, Larry Rubinstein, Jaap Verweij, Martine Van Glabbeke, Allan T. van Oosterom, Michaele C. Christian, Steve G. Gwyther, New Guidelines to Evaluate the Response to Treatment in Solid Tumors JNCI: Journal of the National Cancer Institute. ,vol. 92, pp. 205- 216 ,(2000) , 10.1093/JNCI/92.3.205
I.S. Haslam, K. Jones, T. Coleman, N.L. Simmons, Induction of P-glycoprotein expression and function in human intestinal epithelial cells (T84) Biochemical Pharmacology. ,vol. 76, pp. 850- 861 ,(2008) , 10.1016/J.BCP.2008.07.020
Kaoru Shimokata, Yuichi Ando, Yoshinori Hasegawa, Hideo Saka, Hiroshi Ueoka, Maki Ando, Kei Muro, Akira Yokoyama, Soh Saitoh, Toshiyuki Sawa, Polymorphisms of UDP-Glucuronosyltransferase Gene and Irinotecan Toxicity: A Pharmacogenetic Analysis Cancer Research. ,vol. 60, pp. 6921- 6926 ,(2000)
Hideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa, Jun-ichi Sawada, Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38), an active metabolite of irinotecan (CPT-11), by human UGT1A1 variants, G71R, P229Q, and Y486D. Drug Metabolism and Disposition. ,vol. 31, pp. 108- 113 ,(2003) , 10.1124/DMD.31.1.108
Toru Sugiyama, Michiaki Yakushiji, Takashi Nishida, Kimio Ushijima, Naofumi Okura, Junzo Kigawa, Naoki Terakawa, Irinotecan (CPT-11) combined with cisplatin in patients with refractory or recurrent ovarian cancer Cancer Letters. ,vol. 128, pp. 211- 218 ,(1998) , 10.1016/S0304-3835(98)00065-2
Yoshinori Hasegawa, Takeshi Sarashina, Maki Ando, Chiyoe Kitagawa, Atsuo Mori, Masao Yoneyama, Yuichi Ando, Kaoru Shimokata, Rapid detection of UGT1A1 gene polymorphisms by newly developed Invader assay. Clinical Chemistry. ,vol. 50, pp. 1479- 1480 ,(2004) , 10.1373/CLINCHEM.2004.034694