Effects of metergoline on symptoms in women with premenstrual dysphoric disorder
作者： Catherine A. Roca , Peter J. Schmidt , Mark J. Smith , Merry A. Danaceau , Dennis L. Murphy
DOI: 10.1176/APPI.AJP.159.11.1876
关键词:
摘要: OBJECTIVE: The authors investigated the role of acute serotonergic modulation in efficacy selective serotonin reuptake inhibitors (SSRIs) women with premenstrual dysphoric disorder. METHOD: Patients disorder (whose symptoms had remitted during treatment fluoxetine) and a group unmedicated healthy comparison received receptor antagonist metergoline as part double-blind, placebo-controlled crossover study. RESULTS: patients experienced return 24 hours after but not diphenhydramine (active placebo). no changes mood. CONCLUSIONS: These data support altered transmission SSRI for
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