Fractional CO2 laser treatment for burn scar improvement: A systematic review and meta-analysis.

摘要: Burn injury can cause abnormal healing and pathologic scar formation that significantly impairs patients' ability to return baseline levels of functioning. Quality life be diminished due pain, stiffness, contracture, the psychological burden disfigurement. Traditional therapies such as silicone sheeting compression garments are highly reliant on patient compliance, have not demonstrated satisfactory efficacy. Even more invasive intralesional medication delivery or surgical contracture release high recurrence rates. Recently, fractional CO2 laser therapy has emerged a promising treatment modality for burn scars, but there is lack recent studies aggregates extant data demonstrate outcomes after therapy. To address this, we conducted systematic review meta-analysis determine efficacy lasers in treating found alone yielded statistically significant improvements profiles. There were very few reports adverse effects, most treatments provided outpatient, both practitioners reported satisfaction. By sharing our findings, hope will consider adopting safe cost-effective first-line management.