Three-dimensional axisymmetric flow-focusing device using stereolithography
作者： Yuya Morimoto , Wei-Heong Tan , Shoji Takeuchi
DOI: 10.1007/S10544-008-9243-Y
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摘要: This paper describes a three-dimensional microfluidic axisymmetric flow-focusing device (AFFD) fabricated using stereolithography. Using this method, we can fabricate AFFDs rapidly and automatically without cumbersome alignment needed in conventional methods. The are able to be reproducibly with micro-sized orifice of diameter around 250 μm. device, produce monodisperse water-in-oil (W/O) droplets coefficient variation (CV) less than 4.5%, W/O encapsulated microbes (CV < 4.9%) oil-in-water (O/W) 3.2%) any surface modifications. these range from 54 244 μm respect the flow rate ratio fluids used; results good agreement theoretical behavior. For applications AFFD, demonstrate that devices used double emulsions hydrogel beads.
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